Superselective internal radiation with yttrium-90 microspheres in the management of a chemorefractory testicular liver metastasis.

Abstract	We treated a patient with biopsy-proven, chemotherapy-resistant testicular cancer liver metastasis using Y-90 selective internal radiation treatment. We chose yttrium-90 rather than surgery and ablation due to tumor location and size as well as the patient's clinical history. The result was marked tumor response by positron emission tomography and computed tomography as well as significant improvement of the patient's quality of life accompanied by a substantial decrease of his tumor markers.
Authors	Panagiotis A Sideras, Constantinos T Sofocleous, Lynn A Brody, Robert H Siegelbaum, Rajesh P Shah, Neeta-Pandit Taskar
Journal	Cardiovascular and interventional radiology (Cardiovasc Intervent Radiol) Vol. 35 Issue 2 Pg. 426-9 (Apr 2012) ISSN: 1432-086X [Electronic] United States
PMID	21773859 (Publication Type: Case Reports, Journal Article)
Chemical References	Biomarkers, Tumor Yttrium Radioisotopes
Topics	Biomarkers, Tumor (blood) Drug Resistance, Neoplasm Humans Liver Neoplasms (blood, diagnosis, radiotherapy, secondary) Male Microspheres Middle Aged Quality of Life Remission Induction Testicular Neoplasms (pathology) Yttrium Radioisotopes (administration & dosage)

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