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The post-treatment effects of enterobiasis on the occurrence of enuresis among children in Calabar, Nigeria.

AbstractOBJECTIVE:
To investigate the relationship between enterobiasis and enuresis before and after albendazole therapy among 632 children, aged, 5-14 years, in Calabar, Nigeria.
METHODS:
The scotch tape (cellotape) technique was used for the detection of eggs of Enterobius vermicularis (E. vermicularis) while questionnaire-based interviews were used for screening for anal itching and/or enuresis among study participants. All subjects found positive for Enterobius infection as confirmed by the presence of eggs and those with persistent anal itching (both enuretic and non-enuretic) were treated with 400 mg of albendazole given as a single dose. The treated subjects were re-assessed post-treatment to ascertain whether they were cured and also to determine their enuretic status (for the enuretics).
RESULTS:
The overall prevalences of Enterobius infection, anal itching, and enuresis prior to albendazole therapy were 6.8%, 42.9%, and 35.6% respectively. There was no statistically significant difference in the prevalence of these parameters by the socio-economic class of subjects (P = 0.462, P = 0.647, and P = 0.610, respectively). The pre-treatment prevalences of enuresis among Enterobius and anal itching-positive subjects were 53.5% and 49.8%, respectively versus 34.3% and 24.9%, respectively among their negative counterpart (P = 0.012 and P < 0.001, respectively). Four (20%) out of the 20 enuretic children found Enterobius egg-negative after albendazole therapy were equally cured while 8(40%) had reduction of their enuresis, thus giving a total resolution rate of 60%. Similarly, 64.2% resolution (25% cure and 32.8% reduction) of enuresis was observed amongst 120 anal itching-cured/enuretic children. Enuretic status of the Enterobius-/anal itching-uncured subjects, on the other hand, remained unchanged post-treatment.
CONCLUSIONS:
This study is suggestive of the involvement of E. vermicularis in the aetiology of enuresis in Calabar. Children presenting with, especially, uncomplicated enuresis should be screened for enterobiasis.
AuthorsIquo B Otu-Bassey, Monday F Useh, Anyanwu A Alaribe
JournalAsian Pacific journal of tropical medicine (Asian Pac J Trop Med) Vol. 4 Issue 4 Pg. 315-9 (Apr 2011) ISSN: 2352-4146 [Electronic] India
PMID21771477 (Publication Type: Journal Article)
CopyrightCopyright © 2011 Hainan Medical College. Published by Elsevier B.V. All rights reserved.
Chemical References
  • Anthelmintics
  • Albendazole
Topics
  • Adolescent
  • Albendazole (administration & dosage)
  • Animals
  • Anthelmintics (administration & dosage)
  • Child
  • Child, Preschool
  • Enterobiasis (complications, drug therapy, epidemiology)
  • Enterobius (drug effects, pathogenicity)
  • Enuresis (complications, epidemiology, etiology)
  • Female
  • Humans
  • Male
  • Nigeria (epidemiology)
  • Parasite Egg Count
  • Prevalence
  • Surveys and Questionnaires

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