Abstract | OBJECTIVE: METHODS: The scotch tape (cellotape) technique was used for the detection of eggs of Enterobius vermicularis (E. vermicularis) while questionnaire-based interviews were used for screening for anal itching and/or enuresis among study participants. All subjects found positive for Enterobius infection as confirmed by the presence of eggs and those with persistent anal itching (both enuretic and non-enuretic) were treated with 400 mg of albendazole given as a single dose. The treated subjects were re-assessed post-treatment to ascertain whether they were cured and also to determine their enuretic status (for the enuretics). RESULTS: The overall prevalences of Enterobius infection, anal itching, and enuresis prior to albendazole therapy were 6.8%, 42.9%, and 35.6% respectively. There was no statistically significant difference in the prevalence of these parameters by the socio-economic class of subjects (P = 0.462, P = 0.647, and P = 0.610, respectively). The pre-treatment prevalences of enuresis among Enterobius and anal itching-positive subjects were 53.5% and 49.8%, respectively versus 34.3% and 24.9%, respectively among their negative counterpart (P = 0.012 and P < 0.001, respectively). Four (20%) out of the 20 enuretic children found Enterobius egg-negative after albendazole therapy were equally cured while 8(40%) had reduction of their enuresis, thus giving a total resolution rate of 60%. Similarly, 64.2% resolution (25% cure and 32.8% reduction) of enuresis was observed amongst 120 anal itching-cured/enuretic children. Enuretic status of the Enterobius-/anal itching-uncured subjects, on the other hand, remained unchanged post-treatment. CONCLUSIONS: This study is suggestive of the involvement of E. vermicularis in the aetiology of enuresis in Calabar. Children presenting with, especially, uncomplicated enuresis should be screened for enterobiasis.
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Authors | Iquo B Otu-Bassey, Monday F Useh, Anyanwu A Alaribe |
Journal | Asian Pacific journal of tropical medicine
(Asian Pac J Trop Med)
Vol. 4
Issue 4
Pg. 315-9
(Apr 2011)
ISSN: 2352-4146 [Electronic] India |
PMID | 21771477
(Publication Type: Journal Article)
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Copyright | Copyright © 2011 Hainan Medical College. Published by Elsevier B.V. All rights reserved. |
Chemical References |
- Anthelmintics
- Albendazole
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Topics |
- Adolescent
- Albendazole
(administration & dosage)
- Animals
- Anthelmintics
(administration & dosage)
- Child
- Child, Preschool
- Enterobiasis
(complications, drug therapy, epidemiology)
- Enterobius
(drug effects, pathogenicity)
- Enuresis
(complications, epidemiology, etiology)
- Female
- Humans
- Male
- Nigeria
(epidemiology)
- Parasite Egg Count
- Prevalence
- Surveys and Questionnaires
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