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Massive fetomaternal hemorrhage secondary to intrauterine intravascular transfusion.

AbstractBACKGROUND:
Small-volume fetomaternal hemorrhage is frequently observed after intrauterine transfusion. The Kleihauer-Betke test, the reference method for identifying fetomaternal hemorrhage, cannot be used after intrauterine transfusion, because the adult red blood cells used for transfusion cannot be distinguished from maternal red blood cells.
CASE:
Massive fetomaternal hemorrhage secondary to intrauterine transfusion led to fetal hemorrhagic stroke. We used a method based on blood group identification in the maternal blood to confirm and to quantify fetomaternal hemorrhage.
CONCLUSION:
Fetal stroke may result from severe hypovolemia and low cerebral blood flow caused by fetomaternal hemorrhage, rather than from fetal anemia itself.
AuthorsYaël Levy-Zauberman, Agnès Mailloux, Aminata Kane, Vanina Castaigne, Anne Cortey, Bruno Carbonne
JournalObstetrics and gynecology (Obstet Gynecol) Vol. 118 Issue 2 Pt 2 Pg. 439-442 (Aug 2011) ISSN: 1873-233X [Electronic] United States
PMID21768847 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Blood Group Antigens
  • Fetal Hemoglobin
Topics
  • Blood Group Antigens (isolation & purification)
  • Blood Transfusion, Intrauterine (adverse effects)
  • Cesarean Section
  • Female
  • Fetal Hemoglobin (analysis)
  • Fetomaternal Transfusion (diagnosis, etiology)
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Pregnancy
  • Pregnancy Complications, Hematologic (diagnosis, etiology)
  • Stroke (diagnosis)
  • Treatment Outcome
  • Young Adult

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