Abstract | AIMS: METHODS AND RESULTS: We studied an ST-segment elevation myocardial infarction cohort of 128 consecutive patients (aged 62±11 years) in whom AIVR occurred following reperfusion during primary PCI. Mean systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were determined during periods of AIVR and sinus rhythm. We grouped patients according to the infarct-related artery and the site of the coronary occlusion. AIVR caused an immediate reduction in SBP (130±27 vs. 98±22 mmHg, p<0.001) and DBP (80±19 vs. 69±16 mmHg, p<0.001) and a small increase in heart rate (78±12 vs. 83±11 bpm, p<0.001) as compared to sinus rhythm, irrespective of infarct-related artery. Both absolute as well as relative reduction in SBP were more pronounced in distal than proximal left coronary artery (LCA) occlusions (36±16 vs. 27±12 mmHg, p<0.01, respectively 25±9 vs. 20±8%, p<0.05). These haemodynamic differences between proximal and distal occlusion sites were not observed in the right coronary artery. CONCLUSIONS:
AIVR following reperfusion is associated with marked reduction in both SBP and DBP, irrespective of infarct-related artery. These haemodynamic effects are accompanied by only a very modest increase in heart rate during AIVR. Patients with a culprit lesion in the proximal LCA showed a smaller reduction in systolic blood pressure than distal LCA lesions.
|
Authors | Ronak Delewi, Maurice Remmelink, Martijn Meuwissen, Niels van Royen, Marije M Vis, Karel T Koch, José P S Henriques, Robbert J de Winter, Jan G P Tijssen, Jan Baan Jr, Jan J Piek |
Journal | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
(EuroIntervention)
Vol. 7
Issue 4
Pg. 467-71
(Aug 2011)
ISSN: 1969-6213 [Electronic] France |
PMID | 21764665
(Publication Type: Journal Article)
|
Topics |
- Accelerated Idioventricular Rhythm
(etiology, physiopathology)
- Aged
- Angioplasty, Balloon, Coronary
(adverse effects)
- Blood Pressure
- Female
- Heart Rate
- Hemodynamics
- Humans
- Male
- Middle Aged
- Myocardial Infarction
(pathology, physiopathology, therapy)
- Netherlands
- Time Factors
- Treatment Outcome
|