Outcome predictors in treatment of yaws.

Abstract

To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%). Having low initial titers on Venereal Disease Research Laboratory test and living in a village where yaws baseline incidence was high were associated with increased likelihood of treatment failure.

• Authors: Oriol Mitjà, Russell Hays, Anthony Ipai, David Gubaila, Francis Lelngei, Martin Kirara, Raymond Paru, Quique Bassat
• Journal: Emerging infectious diseases (Emerg Infect Dis) Vol. 17 Issue 6 Pg. 1083-5 (Jun 2011) ISSN: 1080-6059 [Electronic] United States
• PMID: 21749808 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Penicillin G Benzathine

Topics

• Adolescent
• Anti-Bacterial Agents (therapeutic use)
• Child
• Child, Preschool
• Cohort Studies
• Female
• Humans
• Male
• Penicillin G Benzathine (therapeutic use)
• Prognosis
• Skin Ulcer (drug therapy, pathology)
• Treatment Failure
• Treatment Outcome
• Yaws (diagnosis, drug therapy, epidemiology, pathology)