Abstract | BACKGROUND: OBJECTIVE: To describe the respiratory management of patients with chronic neuromuscular diseases admitted to our university hospital ICU for ARF, and the long-term outcomes. METHODS: We retrospectively analyzed patients with chronic neuromuscular diseases admitted to our ICU for a first episode of ARF between January 1, 1996, and February 27, 2007. We assessed severity of illness on ICU admission, respiratory management during ICU stay, and outcomes on June 15, 2008. RESULTS: During the study period, 87 patients (44 with hereditary and 43 with acquired neuromuscular diseases) had their first ARF episode that required ICU admission. In the hereditary-diseases group and the acquired-diseases group, respectively, the rates of NIV use during the ICU stay were 82% and 63% (P = .040), the intubation rates were 30% and 56% (P = .02), and the tracheotomy rates were 9% and 12% (difference not significant). At the final assessment (median 3 years) the mortality rate was 58%, and mortality was not significantly related to the type of neuromuscular disease. At final assessment, 46% of the patients were on NIV and 29% had tracheotomy. CONCLUSIONS: In our ICU, chronic neuromuscular disease is an uncommon cause of ARF, for which we often use NIV. These patients had a low probability of death in the ICU. Long-term outcome was independent of the type of neuromuscular disease.
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Authors | Ghislain Flandreau, Gael Bourdin, Véronique Leray, Frédérique Bayle, Florent Wallet, Bertrand Delannoy, Gérard Durante, Bernard Vincent, Jack Barbier, Jean-François Burle, Sandrine Passant, Jean-Christophe Richard, Claude Guérin |
Journal | Respiratory care
(Respir Care)
Vol. 56
Issue 7
Pg. 953-60
(Jul 2011)
ISSN: 0020-1324 [Print] United States |
PMID | 21740726
(Publication Type: Journal Article)
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Topics |
- Acute Disease
- Adult
- Chronic Disease
- Female
- Humans
- Intensive Care Units
- Male
- Middle Aged
- Neuromuscular Diseases
(complications, mortality)
- Respiration, Artificial
(statistics & numerical data)
- Respiratory Insufficiency
(etiology, mortality, therapy)
- Retrospective Studies
- Tracheotomy
(statistics & numerical data)
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