HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Prevention of postoperative seroma-related morbidity by quilting of latissimus dorsi flap donor site: a systematic review.

AbstractOBJECTIVE:
To systematically analyze the effectiveness of quilting of latissimus dorsi (LD) flap donor site in the prevention of seroma and related morbidities.
METHODS:
All published studies comparing the effectiveness of quilting versus no-quilting of LD flap donor site in the prevention of seroma and related morbidities in patients undergoing breast reconstruction were analysed systemically.
RESULTS:
Five comparative studies on quilting versus no-quilting encompassing 440 patients were suitable for statistical analysis. There was no heterogeneity among trials. Therefore, in the fixed-effects model, quilting was effective in terms of reducing the incidence of donor-site seroma formation, reducing the average volume of the seroma, and reducing the total volume of drained seroma. In addition, quilting did not increase the risk of postoperative complications. Combined quilting and fibrin glue was also effective in reducing the average volume of the seroma and total drained volume of the seroma. Combination of quilting and glue did not influence the incidence of seroma formation at LD flap donor site and overall operative complications.
CONCLUSION:
Quilting of the LD flap donor site is helpful in reducing the incidence of seroma formation, reducing seroma volume, and reducing total drained seroma volume. Combined quilting and fibrin glue further enhances its effectiveness. Quilting with or without fibrin glue may be considered an option in patients undergoing LD flap breast reconstruction to control seroma-related morbidity. However, a major multicenter randomized controlled trial is required to achieve stronger and reliable evidence before recommending it as a routine procedure.
AuthorsM S Sajid, D Betal, N Akhter, I F Rapisarda, R Bonomi
JournalClinical breast cancer (Clin Breast Cancer) Vol. 11 Issue 6 Pg. 357-63 (Dec 2011) ISSN: 1938-0666 [Electronic] United States
PMID21705282 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2011 Elsevier Inc. All rights reserved.
Topics
  • Breast Neoplasms (pathology, surgery)
  • Female
  • Humans
  • Mammaplasty (methods)
  • Postoperative Complications (prevention & control)
  • Seroma (prevention & control)
  • Surgical Flaps
  • Suture Techniques
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: