Abstract |
Ocular cicatricial pemphigoid (OCP) is a progressive cicatrising autoimmune disease affecting the skin and mucous membranes, including ocular surface epithelia. Although systemic immunosuppression is advocated, both progression of ocular surface inflammation and systemic side effects remain a problem. For the treatment of an active OCP, both control of autoimmune reaction and ocular surface reconstruction are necessary. We believe that the combination of intravenous immunoglobulin ( IVIg) and cultivated oral mucosal epithelial transplantation (COMET) is a powerful treatment modality while minimising the risk of postoperative consequences inevitably associated with immunosuppression. A patient with OCP successfully treated by a combination of IVIg and COMET is described here.
|
Authors | Y Uchino, M Uchino, J Shimazaki |
Journal | BMJ case reports
(BMJ Case Rep)
Vol. 2009
( 2009)
ISSN: 1757-790X [Electronic] England |
PMID | 21686527
(Publication Type: Journal Article)
|