Recurrent metanephric stromal tumor in an infant.

Abstract

A 9-month-old boy underwent nephrectomy for a renal mass. Congenital mesoblastic nephroma was diagnosed, and the patient received postoperative chemotherapy. Tumor recurred 6 months later as a scrotal mass. After orchiectomy, diagnosis of metanephric stromal tumor (MST) was made; review of the nephrectomy specimens confirmed this diagnosis. No additional treatment was given, and the child is alive and well 31 months later. Taking into account the histopathological entity of MST in the differential diagnosis of stromal renal tumors in childhood can spare the patient further, potentially toxic, treatment even in the case of relapse, as reported here for the first time.

• Authors: Maria Debora De Pasquale, Francesca Diomedi-Camassei, Annalisa Serra, Renata Boldrini, Alessandro Inserra, Paolo Caione, Alessandro Jenkner
• Journal: Urology (Urology) Vol. 78 Issue 6 Pg. 1411-3 (Dec 2011) ISSN: 1527-9995 [Electronic] United States
• PMID: 21683990 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2011 Elsevier Inc. All rights reserved.

Chemical References

• Dactinomycin
• Vincristine

Topics

• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Dactinomycin (administration & dosage)
• Diagnosis, Differential
• Humans
• Infant
• Kidney Neoplasms (drug therapy, pathology, surgery)
• Male
• Nephroma, Mesoblastic (pathology, surgery)
• Stromal Cells (pathology)
• Testicular Neoplasms (pathology, surgery)
• Vincristine (administration & dosage)