Abstract |
A single administration of amixin followed by oral infection with mouse hepatitis virus provided protection of 40%-50% animals for 72 hours and normalized the interferon status. In parallel with decreasing level of virus-induced endogenous interferon the interferon-inhibiting activity of lymphocytes of the infected animals increased and approached normal levels.
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Authors | S S Grigorian, A M Ivanova, F I Ershov |
Journal | Voprosy virusologii
(Vopr Virusol)
1990 Mar-Apr
Vol. 35
Issue 2
Pg. 138-40
ISSN: 0507-4088 [Print] Russia (Federation) |
Vernacular Title | Protivovirusnaia aktivnost' amiksina i ego vliianie na interferonovyÄ status pri gepatitie mysheÄ. |
PMID | 2167565
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Antiviral Agents
- Fluorenes
- Interferon Inducers
- Interferon Type I
- Interferon-gamma
- Tilorone
|
Topics |
- Animals
- Antiviral Agents
(therapeutic use)
- Drug Evaluation, Preclinical
- Fluorenes
(therapeutic use)
- Hepatitis, Viral, Animal
(blood, drug therapy)
- Interferon Inducers
(therapeutic use)
- Interferon Type I
(blood)
- Interferon-gamma
(blood)
- Male
- Mice
- Murine hepatitis virus
- Tilorone
(analogs & derivatives, therapeutic use)
- Time Factors
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