[Phrynoderma secondary to vitamin A deficiency in a patient with biliopancreatic diversion].

Abstract

Biliopancreatic diversion (BPD) is a malabsorptivebariatric procedure can lead to the development of several nutritional complications, including fat-soluble vitamins deficiencies. Routine supplementation with vitamins and trace elements and a close follow-up long-term can prevent these nutritional risks. Vitamin A participates in ocular metabolism, epithelial differentiation, growth, and embryogenesis. Have been described several cases of ophthalmological and fetal complications associated with vitamin A deficiency in patients who have undergone BPD. Few information exists in literature about dermatologic manifestations that may occur in these patients. Phrynoderma is a type of follicular hyperkeratosis located on the extensor surfaces of the extremities whose main cause is vitamin A deficiency. We report an exceptional case of severe cutaneous and ocular complications in a patient who had undergone BPD with poor adherence to treatment and postoperative follow-up. Our patient presented simultaneously the characteristic skin lesions of phrynoderma with nytalopia and xerophthalmia in a setting of low serum levels of vitamin A. Treatment with high doses vitamin A obtained the resolution of both processes. We review and discuss the relationship between phrynoderma, malnutrition and vitamin A deficiency.

• Authors: J Ocón Bretón, M C Cabrejas Gómez, J Altermir Trallero
• Journal: Nutricion hospitalaria (Nutr Hosp) 2011 Mar-Apr Vol. 26 Issue 2 Pg. 421-4 ISSN: 1699-5198 [Electronic] Spain
• Vernacular Title: Frinoderma secundario a déficit de vitamina A en un paciente con derivación biliopancreática.
• PMID: 21666984 (Publication Type: English Abstract, Journal Article)

Chemical References

• Vitamins
• Vitamin A

Topics

• Biliopancreatic Diversion (adverse effects)
• Eye Diseases (etiology)
• Humans
• Keratosis (etiology)
• Malabsorption Syndromes (etiology)
• Male
• Malnutrition (etiology)
• Middle Aged
• Patient Compliance
• Postoperative Complications (pathology, therapy)
• Skin (pathology)
• Vitamin A (therapeutic use)
• Vitamin A Deficiency (complications, etiology)
• Vitamins (therapeutic use)
• Xerophthalmia (etiology, pathology)