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[New treatments in vascular diseases other than age related macular degeneration].

Abstract
Recent multicenter randomized studies about persistent macular edema in venous occlusions provided us with interesting results. Until now, the standard of care treatment of macular edema due to branch vein occlusion remained grid laser in contrast with central vein occlusion where the absence of treatment was still recommended. Score, Geneva, Bravo and Cruise studies recently provided us with the following results. Score study found triamcinolone to be interesting to treat macular edema due to central vein occlusion but not from branch occlusion. Geneva study assessed the effect of a delivery system of dexamethasone to treat macular edema due to venous occlusion whatever the clinical form with an improvement of visual acuity. Cruise and Bravo studies assessed the effect of ranubizumab, which was found to improve the visual acuity of macular edema due to either central or branch vein occlusions. At this stage we need comparative studies to precise the indication of these different approaches that remain perhaps complementary of laser treatment.
AuthorsC Creuzot-Garcher
JournalJournal francais d'ophtalmologie (J Fr Ophtalmol) Vol. 34 Issue 7 Pg. 502-7 (Sep 2011) ISSN: 1773-0597 [Electronic] France
Vernacular TitleInnovations thérapeutiques dans les pathologies vasculaires et néovasculaires hors DMLA.
PMID21658790 (Publication Type: English Abstract, Journal Article)
CopyrightCopyright © 2011 Elsevier Masson SAS. All rights reserved.
Chemical References
  • Adrenal Cortex Hormones
  • Angiogenesis Inhibitors
  • Dexamethasone
Topics
  • Adrenal Cortex Hormones (therapeutic use)
  • Angiogenesis Inhibitors (therapeutic use)
  • Dexamethasone (administration & dosage)
  • Humans
  • Macular Degeneration
  • Macular Edema (drug therapy, etiology)
  • Retinal Vein Occlusion (complications)

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