[Seroprevalence of human parvovirus B 19 antibodies (Sticker's disease/erythema infectiosum) in the DRG population].

Abstract

We tested 638 human sera of all age groups (patients and blood donors) from the northern area of the G.D.R. and found 216 cases (33.9%) of specific parvovirus B19 antibodies (IgG) by antibody capture ELISA. The seroprevalence rose to 36.7% when the 18 parvo B19-IgM- and/or parvo B19-DNA-positive results were included. The antibody prevalence was 24.9 (27.8% resp.) in the 0-10 years group and increased continuously in the following age groups up to 61.1% (69.4% resp.) in the 51-60 years group. 50% of the newborn infants showed parvo B19-IgG-antibodies in the cord blood (of maternal origin). No sex differences in seroprevalence were observed. Parvovirus B19 is obviously very prevalent in the G.D.R. population. The main immunization occurs in the first 30-40 years of life but infection with parvo B19 at a later age is also well documented. Hence it follows that 35-45% of all G.D.R. females of reproductive age are susceptible to a parvovirus B19 infection.

• Authors: S Wiersbitzky, T F Schwarz, R Bruns, G Jäger, S Bittner, H Weidemann, F Deinhardt, B Hottenträger, E Abel, L Ladstätter
• Journal: Kinderarztliche Praxis (Kinderarztl Prax) Vol. 58 Issue 4 Pg. 185-9 (Apr 1990) ISSN: 0023-1495 [Print] Germany
• Vernacular Title: Seroprävalenz von Antikörpern gegen das humane Parvovirus B 19 (Ringelröteln/Erythema infectiosum) in der DDR-Bevölkerung.
• PMID: 2164118 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antibodies, Viral

Topics

• Adolescent
• Adult
• Antibodies, Viral (isolation & purification)
• Child
• Child, Preschool
• Erythema (immunology)
• Germany, East (epidemiology)
• Humans
• Infant
• Infant, Newborn
• Middle Aged
• Parvoviridae (immunology)
• Parvoviridae Infections (epidemiology, immunology)
• Population Surveillance