Breast metastatic localization of signet-ring cell gastric carcinoma.

Abstract

Metastatic tumors in the breast are quite rare and constitute 0,5 to 6% of all breast malignancies. They often occur in a polymetastatic context. Gastrointestinal lesions rarely metastasize to the breast. The first case of a metastasis deposit to the breast and ovary from gastric signet-ring cell carcinoma was reported in the literature in 1999. Since this report, only 5 cases have been reported. We present a case report of a 37-year-old woman who complained of a lump in the left breast. Two months earlier, the woman underwent a subtotal gastrectomy and a total hysterectomy with double anexectomy, which histologically was diagnosed of gastric signet-ring carcinoma, disseminated with Krukenberg's tumor. In those days, the patient was following a chemotherapy treatment. A core needle biopsy of the lesion in left breast revealed cells with signet-ring features, with probably gastric origin.

• Authors: C Parrell Soler, A Palacios Marqués, L Saco López, R Bermejo De Las Heras, S Pertusa Martínez
• Journal: ISRN obstetrics and gynecology (ISRN Obstet Gynecol) Vol. 2011 Pg. 426150 ( 2011) ISSN: 2090-4444 [Electronic] United States
• PMID: 21637360 (Publication Type: Case Reports)