Abstract | BACKGROUND: CASE PRESENTATION: CONCLUSIONS: The detection of IL-11-induced CLS supports the hypothesis that CLS could be a severe side effect of IL-11 treatment in some patients. These two case reports also demonstrate that patients with hepatic carcinoma who experience this rare form of CLS after treatment with IL-11 seem to respond to a therapeutic regimen that involves hydroxyethyl starch, albumin, and diuretic therapy. Liver cancer patients might be more susceptible to CLS because of poor liver function and hypersplenia. In addition, bleeding after RFA might be a further inducer of CLS.
|
Authors | Wang Kai-Feng, Pan Hong-Ming, Lou Hai-Zhou, Shen Li-Rong, Zhu Xi-Yan |
Journal | BMC cancer
(BMC Cancer)
Vol. 11
Pg. 204
(May 27 2011)
ISSN: 1471-2407 [Electronic] England |
PMID | 21619578
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Aged
- Capillary Leak Syndrome
(chemically induced, diagnosis, pathology, therapy)
- Carcinoma, Hepatocellular
(complications)
- Humans
- Interleukin-11
(pharmacology)
- Liver Neoplasms
(complications)
- Male
- Middle Aged
- Thrombocytopenia
(drug therapy, etiology)
- Treatment Outcome
|