[Treatment of a positive Rhesus D neonate born of a mother with idiopathic thrombopenic purpura with anti-D immunoglobulins (Rh O)].

Abstract

A Rhesus D positive infant, born at 37 weeks of gestational age, admitted for neonatal passive immune thrombocytopenia was given 3 intravenous anti-Rhesus D immunoglobulin infusions at 3 weeks of age. This thrombocytopenia which had not responded to conventional therapy improved after the third of anti-Rhesus D immunoglobulin infusion, but the efficacy of this treatment could not be proven in this case report. However, the tolerance was good. No side-effects (jaundice, severe anemia) were observed.

• Authors: H di Maria, F Parnet Mathieu, D Rio di Maria, P Maigret, R Gire, F Guillot, G Lasfargues, Y Brossard
• Journal: Archives francaises de pediatrie (Arch Fr Pediatr) Vol. 47 Issue 2 Pg. 125-7 (Feb 1990) ISSN: 0003-9764 [Print] France
• Vernacular Title: Traitement d'un nouveau-né Rhésus D positif né de mère atteinte d'un purpura thrombopénique idiopathique par immunoglobulines anti-D (Rh O).
• PMID: 2158285 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Immunoglobulins
• Rh-Hr Blood-Group System
• Rho(D) Immune Globulin

Topics

• Erythroblastosis, Fetal (immunology, therapy)
• Female
• Gestational Age
• Humans
• Immunoglobulins (administration & dosage)
• Infant, Newborn
• Perfusion
• Pregnancy
• Pregnancy Complications (immunology)
• Rh-Hr Blood-Group System (immunology)
• Rho(D) Immune Globulin
• Thrombocytopenia (genetics, therapy)