Tc-99m exametazime (HMPAO)-labeled leukocyte scintigraphy in premature infants: detection and localization of necrotic enterocolitis and osteomyelitis.

Abstract

Two cases of successful detection of inflammatory foci using Tc-99m exametazime (HMPAO)-labeled leukocyte scintigraphy in premature infants were reported. Necrotizing enterocolitis was detected in a child with a body weight of 1.6 kg. Scintigraphy confirmed a neonatal osteomyelitis in the distal part of the leg of another patient weighing 2.2 kg. These 2 cases indicate that it is feasible to perform Tc-99m HMPAO-labeled leukocyte scintigraphy even if the blood sample volume is lower than the minimal volumes required by the guidelines for pediatric patients.

• Authors: Pavel Koranda, Jarmila Drymlová, Tomáš Malý, Lumír Kantor, Jaroslav Ptáček, Miroslav Mysliveček
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 36 Issue 6 Pg. e35-6 (Jun 2011) ISSN: 1536-0229 [Electronic] United States
• PMID: 21552012 (Publication Type: Case Reports, Journal Article)

Chemical References

• Technetium Tc 99m Exametazime

Topics

• Enterocolitis, Necrotizing (complications, diagnostic imaging, pathology, physiopathology)
• Female
• Humans
• Infant
• Isotope Labeling
• Leukocytes (diagnostic imaging)
• Osteomyelitis (blood, complications, diagnostic imaging, pathology, physiopathology)
• Pregnancy
• Premature Birth (diagnostic imaging, pathology, physiopathology)
• Radionuclide Imaging
• Technetium Tc 99m Exametazime