Partial internal biliary diversion: a solution for intractable pruritus in progressive familial intrahepatic cholestasis type 1.

Abstract

Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders. Progressive familial intrahepatic cholestasis (PFIC) is an inherited disorder of impaired bile acid transport and excretion, which presents with jaundice and pruritus in the first few months of life and progresses to cirrhosis by infancy or adolescence. We report a child with PFIC type 1 who underwent internal biliary diversion for intractable pruritus and was relieved of his symptoms.

• Authors: Ramaswamy Ganesh, Natarajan Suresh, Malathi Sathiyasekeran, Priya Ramachandran
• Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association (Saudi J Gastroenterol) 2011 May-Jun Vol. 17 Issue 3 Pg. 212-4 ISSN: 1998-4049 [Electronic] India
• PMID: 21546727 (Publication Type: Case Reports, Journal Article)

Topics

• Anastomosis, Surgical
• Bile Canaliculi (pathology)
• Biliary Tract Surgical Procedures (methods)
• Child
• Cholestasis, Intrahepatic (complications, pathology, surgery)
• Humans
• Liver (pathology)
• Male
• Pruritus (etiology, surgery)