Impact of hepatitis C in mortality in patients on hemodialysis.

Abstract

OBJECTIVE:

Cardiovascular diseases are the most important causes of mortality in patients with end-stage renal disease. However, viral infections (hepatitis B and C) have acquired great importance for patients undergoing hemodialysis, because they affect patients' survival and increase morbidity and mortality. This study aimed at assessing the influence of hepatitis C on the mortality of patients undergoing hemodialysis.

METHODS:

This is a non-concurrent cohort study during a period of ten years.

RESULTS:

Each cohort comprised 74 patients. Hepatitis C did not increase the risk of death, and the survival of infected patients was better than that of patients without hepatitis C. The one-year and five-year survivals of non-infected patients were 93.9% and 52.3%, respectively, while those of noninfected patients were 95.5% and 73.1%, respectively (Cox-Mantel log-rank, p = 0.02).

CONCLUSION:

No increase in mortality risk was observed. Hepatitis C did not correlate with an increase in mortality in patients with end-stage renal disease undergoing hemodialysis.

• Authors: Cristian Paul Leon Rabanal, Javier Cieza Zevallos, Roberto Cieza Cusato
• Journal: Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia (J Bras Nefrol) Vol. 32 Issue 4 Pg. 335-9 (Dec 2010) ISSN: 2175-8239 [Electronic] Brazil
• PMID: 21541447 (Publication Type: Journal Article)

Topics

• Cohort Studies
• Female
• Hepatitis C (mortality)
• Humans
• Male
• Middle Aged
• Renal Dialysis (mortality)