Abstract |
We present a 79-year-old man with a 2-year history of Bowen's disease. The 10 × 10 plaque was located on the right frontotemporal area. The patient was treated with two photodynamic therapy ( PDT) sessions, performed 1 week apart, followed by five times per week application of imiquimod 5% cream for 6 consecutive weeks. Complete clinical and histological response was achieved 3 months after treatment was completed. The patient remains recurrence free 12 months after treatment. Cosmetic outcome was evaluated as fair because of residual erythema. Long-term follow-up is mandatory for assessment of recurrences. Further studies are needed in order to confirm the improved outcome using the combination of PDT and imiquimod cream.
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Authors | Eleni Sotiriou, Aimilios Lallas, Zoi Apalla, Demetris Ioannides |
Journal | Photodermatology, photoimmunology & photomedicine
(Photodermatol Photoimmunol Photomed)
Vol. 27
Issue 3
Pg. 164-6
(Jun 2011)
ISSN: 1600-0781 [Electronic] England |
PMID | 21535173
(Publication Type: Case Reports, Journal Article)
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Copyright | © 2011 John Wiley & Sons A/S. |
Chemical References |
- Aminoquinolines
- Antineoplastic Agents
- Imiquimod
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Topics |
- Administration, Topical
- Aged
- Aminoquinolines
(administration & dosage)
- Antineoplastic Agents
(administration & dosage)
- Bowen's Disease
(drug therapy, pathology)
- Head and Neck Neoplasms
(drug therapy, pathology)
- Humans
- Imiquimod
- Male
- Photochemotherapy
- Remission Induction
- Skin Neoplasms
(drug therapy, pathology)
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