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Tryptophan for the treatment of excessive daytime sleepiness in Prader-Willi syndrome.

Abstract
An 8-year old girl with Prader-Willi Syndrome presenting with excessive daytime sleepiness improved following treatment with tryptophan; possibly by consolidation of her fragmented sleep. Improvement was recorded on a follow-up sleep study, one year after initiating treatment with tryptophan. We conclude that tryptophan may be an useful medication for excessive sleepiness in children with Prader-Willi Syndrome.
AuthorsYu Jin Lee, Shai Marcu, Glenn Berall, Colin M Shapiro
JournalIndian pediatrics (Indian Pediatr) Vol. 48 Issue 4 Pg. 319-21 (Apr 2011) ISSN: 0974-7559 [Electronic] India
PMID21532101 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Tryptophan
Topics
  • Child
  • Disorders of Excessive Somnolence (complications, drug therapy)
  • Female
  • Follow-Up Studies
  • Humans
  • Prader-Willi Syndrome (complications)
  • Treatment Outcome
  • Tryptophan (therapeutic use)

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