Abstract | INTRODUCTION: OBJECTIVE: To identify the aetiology of chronic dacryocystitis and to determine their antimicrobial susceptibility pattern. MATERIALS AND METHODS: A cross - sectional study was undertaken including 120 lacrimal swab materials collected from patients aged above 15 years suffering from chronic dacryocystitis. STATISTICS: Data analysis was done by using software "Win pepi'' ver 7.9. RESULTS: The bacteria of eight different species were isolated from 76.66 % (92/120) culture positive samples. 85.86 % showed a single and 14.13 % showed a mixed growth pattern. Coagulase negative staphylococci were the most common bacteria (P= 0.018) accounting for 33.96 % followed by Staphylococcus aureus (25.46 %), Streptococcus pneumoniae ( 19.81 % ), Streptococci viridans (5.66 %), Escherichia coli (5.66 %), Haemophilus spp ( 4.71 % ), Streptococcus pyogenes (3.77 %) and Bacillus spp (0.94 % ). Staphylococcus aureus were the most predominant bacteria in mixed growth. Rate of infection was higher in males 81.39 % than in females 74.02 %. Infection was higher in the age group of above 31 years. In the antimicrobial susceptibility test, except staphylococcus aureus, all the Gram positive isolates were 100 % sensitive to chloramphenicol and were least sensitive to tobramycin, but Gram negative isolates were equally sensitive to Chloramphenicol and Nalidixic acid. CONCLUSION:
Coagulase negative staphylococci are the most frequently isolated bacteria. Staphylococcus aureus is predominantly found in mixed growth. Chloramphenicol is the most effective drug of choice for chronic dacryocystitis.
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Authors | M Chaudhary, A Bhattarai, S K Adhikari, D R Bhatta |
Journal | Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
(Nepal J Ophthalmol)
2010 Jul-Dec
Vol. 2
Issue 2
Pg. 105-13
ISSN: 2072-6805 [Print] Nepal |
PMID | 21505526
(Publication Type: Journal Article)
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Copyright | © Nepal Ophthalmic Society. |
Chemical References |
- Anti-Bacterial Agents
- Anti-Infective Agents
- Nalidixic Acid
- Chloramphenicol
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Topics |
- Adult
- Anti-Bacterial Agents
(therapeutic use)
- Anti-Infective Agents
(therapeutic use)
- Chloramphenicol
(therapeutic use)
- Chronic Disease
- Cross-Sectional Studies
- Dacryocystitis
(drug therapy, microbiology)
- Drug Resistance, Bacterial
- Eye Infections, Bacterial
(diagnosis, drug therapy)
- Female
- Humans
- Lacrimal Apparatus
(microbiology)
- Lacrimal Apparatus Diseases
(drug therapy, microbiology)
- Male
- Microbial Sensitivity Tests
- Middle Aged
- Nalidixic Acid
(therapeutic use)
- Nepal
- Staphylococcal Infections
(diagnosis, drug therapy)
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