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Bacteriology and antimicrobial susceptibility of adult chronic dacryocystitis.

AbstractINTRODUCTION:
Chronic dacryocystitis results in chronic infection and inflammation of the lacrimal sac.
OBJECTIVE:
To identify the aetiology of chronic dacryocystitis and to determine their antimicrobial susceptibility pattern.
MATERIALS AND METHODS:
A cross - sectional study was undertaken including 120 lacrimal swab materials collected from patients aged above 15 years suffering from chronic dacryocystitis.
STATISTICS:
Data analysis was done by using software "Win pepi'' ver 7.9.
RESULTS:
The bacteria of eight different species were isolated from 76.66 % (92/120) culture positive samples. 85.86 % showed a single and 14.13 % showed a mixed growth pattern. Coagulase negative staphylococci were the most common bacteria (P= 0.018) accounting for 33.96 % followed by Staphylococcus aureus (25.46 %), Streptococcus pneumoniae ( 19.81 % ), Streptococci viridans (5.66 %), Escherichia coli (5.66 %), Haemophilus spp ( 4.71 % ), Streptococcus pyogenes (3.77 %) and Bacillus spp (0.94 % ). Staphylococcus aureus were the most predominant bacteria in mixed growth. Rate of infection was higher in males 81.39 % than in females 74.02 %. Infection was higher in the age group of above 31 years. In the antimicrobial susceptibility test, except staphylococcus aureus, all the Gram positive isolates were 100 % sensitive to chloramphenicol and were least sensitive to tobramycin, but Gram negative isolates were equally sensitive to Chloramphenicol and Nalidixic acid.
CONCLUSION:
Coagulase negative staphylococci are the most frequently isolated bacteria. Staphylococcus aureus is predominantly found in mixed growth. Chloramphenicol is the most effective drug of choice for chronic dacryocystitis.
AuthorsM Chaudhary, A Bhattarai, S K Adhikari, D R Bhatta
JournalNepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH (Nepal J Ophthalmol) 2010 Jul-Dec Vol. 2 Issue 2 Pg. 105-13 ISSN: 2072-6805 [Print] Nepal
PMID21505526 (Publication Type: Journal Article)
Copyright© Nepal Ophthalmic Society.
Chemical References
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Nalidixic Acid
  • Chloramphenicol
Topics
  • Adult
  • Anti-Bacterial Agents (therapeutic use)
  • Anti-Infective Agents (therapeutic use)
  • Chloramphenicol (therapeutic use)
  • Chronic Disease
  • Cross-Sectional Studies
  • Dacryocystitis (drug therapy, microbiology)
  • Drug Resistance, Bacterial
  • Eye Infections, Bacterial (diagnosis, drug therapy)
  • Female
  • Humans
  • Lacrimal Apparatus (microbiology)
  • Lacrimal Apparatus Diseases (drug therapy, microbiology)
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Nalidixic Acid (therapeutic use)
  • Nepal
  • Staphylococcal Infections (diagnosis, drug therapy)

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