Gastric varices with remarkable collateral veins in valpronic Acid-induced chronic pancreatitis.

Abstract

Valproic acid (VPA) is a commonly prescribed and approved treatment for epilepsy, including Angelman syndrome, throughout the world. However, the long-term administration of drugs like VPA is associated with the possible development of gastric varices and splenic obstruction as a result of chronic pancreatitis. Such cases can be difficult to treat using endoscopy or interventional radiology because of hemodynamic abnormalities; therefore, surgical treatment is often necessary.

• Authors: Y Hattori, T Higurashi, H Takahashi, M Inamori, Y Abe, Y Rino, A Nakajima
• Journal: Case reports in gastroenterology (Case Rep Gastroenterol) Vol. 2 Issue 2 Pg. 279-82 (Aug 19 2008) ISSN: 1662-0631 [Print] Switzerland
• PMID: 21490900 (Publication Type: Case Reports)