Treatment of onychomycosis with a bifonazole-urea combination.

Abstract	A clinical trial has been conducted to assess the efficacy of 1% bifonazole and 40% urea ointment for 2 weeks followed by 1% bifonazole cream for one month in the topical treatment of onychomycosis. Thinning and total avulsion of the nails occurred in 97% of 30 patients with candidal onychomycosis and regrowth of a normal appearing nail was found in 92% of 26 patients. Failure rate was 4% and recurrence rate was 12% in 26 patients. Results of the treatment was followed up for 12 weeks. Side effects were negligible.
Authors	F S Hardjoko, S Widyanto, I Singgih, J Susilo
Journal	Mycoses (Mycoses) Vol. 33 Issue 4 Pg. 167-71 (Apr 1990) ISSN: 0933-7407 [Print] Germany
PMID	2146498 (Publication Type: Journal Article)
Chemical References	Antifungal Agents Imidazoles Ointments Urea bifonazole
Topics	Administration, Topical Adolescent Adult Antifungal Agents (therapeutic use) Child Drug Therapy, Combination Female Humans Imidazoles (therapeutic use) Male Middle Aged Ointments Onychomycosis (drug therapy) Urea (therapeutic use)

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