Abstract | BACKGROUND: The use of biomarkers has been demonstrated useful in many acute diseases both for diagnosis, prognosis and risk stratification. OBJECTIVES: The purpose of this review is to analyze several biomarkers of potential use in patients referring to Emergency Department with acute dyspnea. STATE OF THE ART: PERSPECTIVES: Further studies with randomized controlled clinical trials will be needed to prove the theoretical clinical advantages offered by a shortness of breath biomarkers in terms of diagnostic, prognostic, cost effective work-up and management of patients with acute dyspnea. CONCLUSIONS: A multimarker pannel approach performed by rapid and accurate assays could be useful for emergency physicians to promptly identify different causes of dyspnea thus managing to improve diagnosis, treatment and risk stratification.
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Authors | C S Gori, L Magrini, F Travaglino, S Di Somma |
Journal | European review for medical and pharmacological sciences
(Eur Rev Med Pharmacol Sci)
Vol. 15
Issue 2
Pg. 229-40
(Feb 2011)
ISSN: 1128-3602 [Print] Italy |
PMID | 21434492
(Publication Type: Journal Article, Review)
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Chemical References |
- Biomarkers
- CALCA protein, human
- Fibrin Fibrinogen Degradation Products
- Peptide Fragments
- Protein Precursors
- Troponin T
- fibrin fragment D
- midregional pro-atrial natriuretic peptide, human
- pro-brain natriuretic peptide (1-76)
- Natriuretic Peptide, Brain
- Adrenomedullin
- Atrial Natriuretic Factor
- Calcitonin
- Calcitonin Gene-Related Peptide
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Topics |
- Acute Disease
- Adrenomedullin
(blood)
- Atrial Natriuretic Factor
(blood)
- Biomarkers
(blood)
- Calcitonin
(blood)
- Calcitonin Gene-Related Peptide
- Dyspnea
(blood, diagnosis)
- Fibrin Fibrinogen Degradation Products
(analysis)
- Humans
- Natriuretic Peptide, Brain
(blood)
- Peptide Fragments
(blood)
- Protein Precursors
(blood)
- Troponin T
(blood)
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