Abstract | BACKGROUND AND OBJECTIVES: PATIENTS AND METHODS: Recurrent stroke patterns were studied in 605 consecutive patients admitted with a second or further ischemic stroke to the Department of Neurology of the Sagrat Cor Hospital of Barcelona over a 17 year period. Demographic, risk factors, clinical, neuroimaging and outcome variables were analyzed and compared with patients with first-ever cerebral infarction (n=2.099) to identify predictors of ischemic recurrent stroke. Significant variables were entered into a multivariate logistic regression analysis. RESULTS: Ischemic recurrent strokes accounted for 22.4% of all acute consecutive ischemic strokes. Frequency of ischemic stroke recurrence were significantly different among ischemic stroke subtypes: 26.2% in atherothrombotic, 24.4% in cardioembolic, 21.8% in lacunar stroke, 15.8% in infarcts of unusual etiology and 12% infarctions of uncertain etiology. The overall in-hospital mortality and symptom free at discharge in recurrent vs. non-recurrent stroke patients rate was 16.2 vs. 12% (p=0.005) and 17.8 vs. 27.3% (p=0.0001) respectively. Previous intracerebral hemorrhage (OR=3.07; 95% CI, 1.51-6.25), intermittent claudication (OR=1.39; 95% CI, 1.01-1.90), arterial hypertension (OR=1.32; 95% CI, 1.09-1.59), diabetes mellitus (OR=1.26; 95% CI, 1.02-1.56), age (OR=1.02; 95% CI, 1.01-1.03), female gender (OR=0.63; 95% CI, 0.52-0.77), headache (OR=0.62; 95% CI, 0.44-0.87) and bulbar topography (OR=0.21; 95% CI, 0.05-0.89) were independent clinical variables related to ischemic stroke recurrence. CONCLUSIONS:
|
Authors | Adrià Arboix, Joan Massons, Luís García-Eroles, Emili Comes, Miquel Balcells, Montserrat Oliveres |
Journal | Medicina clinica
(Med Clin (Barc))
Vol. 137
Issue 12
Pg. 541-5
(Nov 12 2011)
ISSN: 1578-8989 [Electronic] Spain |
Vernacular Title | Infartos cerebrales recurrentes: estudio de 605 pacientes. |
PMID | 21420134
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
|
Copyright | Copyright © 2010 Elsevier España, S.L. All rights reserved. |
Topics |
- Aged
- Aged, 80 and over
- Brain Damage, Chronic
(epidemiology, etiology)
- Brain Ischemia
(epidemiology)
- Cerebral Infarction
(epidemiology)
- Diabetes Mellitus
(epidemiology)
- Female
- Heart Diseases
(epidemiology)
- Hospital Mortality
- Humans
- Hypertension
(epidemiology)
- Intermittent Claudication
(epidemiology)
- Ischemic Attack, Transient
(epidemiology)
- Length of Stay
(statistics & numerical data)
- Male
- Middle Aged
- Prognosis
- Recurrence
- Risk Factors
- Spain
(epidemiology)
- Treatment Outcome
|