Abstract | BACKGROUND: OBJECTIVES: ANIMALS: METHODS: Retrospective case review. Information obtained included signalment, body weight, clinical signs, drug regimen, treatment duration, time to clinical remission, and laboratory results. RESULTS: CONCLUSIONS:
Fluconazole is associated with survival to clinical remission in 75% of dogs with blastomycosis. Although dogs receiving fluconazole were treated longer, drug costs were one-third those of itraconazole. Hepatotoxicosis, as estimated by increases in serum ALT activity, can be observed with similar incidence for both drugs.
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Authors | A S W Mazepa, L A Trepanier, D S Foy |
Journal | Journal of veterinary internal medicine
(J Vet Intern Med)
2011 May-Jun
Vol. 25
Issue 3
Pg. 440-5
ISSN: 1939-1676 [Electronic] United States |
PMID | 21418325
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright © 2011 by the American College of Veterinary Internal Medicine. |
Chemical References |
- Antifungal Agents
- Itraconazole
- Fluconazole
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Topics |
- Animals
- Antifungal Agents
(economics, therapeutic use)
- Blastomycosis
(drug therapy, economics, veterinary)
- Dog Diseases
(drug therapy, economics)
- Dogs
- Female
- Fluconazole
(economics, therapeutic use)
- Itraconazole
(economics, therapeutic use)
- Male
- Retrospective Studies
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