Pulp repair after pulpotomy using different pulp capping agents: a comparative histologic analysis.

Abstract

PURPOSE:

This study's purpose was to histologically evaluate the repair of rat tissue after pulpotomy and covering the pulp tissue with Copaifera langsdorffi oil resin, green propolis extract, fibrin sponge and iodoform-based paste.

METHODS:

Pulpotomies were performed in the maxillary and mandibular first molars of 21 Wistar rats (84 total teeth). The access cavities were sealed with Coltosol, and histological evaluations were performed at 24 hours, 15 days, and 30 days postoperatively.

RESULTS:

For all experimental periods and materials, an inflammatory response constituted predominantly by neutrophils was observed, being of milder intensity for the Copaifera langsdorffii oil-resin group and more severe for the fibrin sponge group, which exhibited periapical microabscesses. Necrosis was observed in all groups, and its extension increased with time, except for teeth protected with Copaifera langsdorffii oil-resin. Formation of a mineralized tissue barrier in the pulp exposure area occurred only in the Copaifera langsdorffii oil-resin group. Other findings, such as vascular congestion, edema, and hemorrhage, were observed in all cases.

CONCLUSIONS:

The inflammatory response was less severe, the area of pulp necrosis was smaller, and more frequent formation of a mineralized tissue barrier was noted after pulpotomy was performed with Copaifera langsdorffii oil-resin compared to the other materials tested.

• Authors: Raimunda Vilmar Evangelista Lima, Mabel Rodrigues Alves Esmeraldo, Maria Goretti Freire de Carvalho, Patrícia Teixeira de Oliveira, Rejane Andrade de Carvalho, Francisco Lopes da Silva Jr, Edja Maria Melo de Brito Costa
• Journal: Pediatric dentistry (Pediatr Dent) 2011 Jan-Feb Vol. 33 Issue 1 Pg. 14-8 ISSN: 0164-1263 [Print] United States
• PMID: 21406142 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Fibrin Tissue Adhesive
• Hydrocarbons, Iodinated
• Plant Extracts
• Plant Oils
• Pulp Capping and Pulpectomy Agents
• Propolis
• iodoform

Topics

• Animals
• Dental Pulp (physiology)
• Dental Pulp Necrosis (etiology)
• Dentin, Secondary (metabolism)
• Fabaceae
• Female
• Fibrin Tissue Adhesive (therapeutic use)
• Hydrocarbons, Iodinated (therapeutic use)
• Periapical Abscess (etiology)
• Phytotherapy
• Plant Extracts (therapeutic use)
• Plant Oils (therapeutic use)
• Propolis (therapeutic use)
• Pulp Capping and Pulpectomy Agents (therapeutic use)
• Pulpitis (etiology)
• Pulpotomy (adverse effects)
• Random Allocation
• Rats
• Rats, Wistar