[Pain syndrome in patients with spastic torticollis before and after the treatment with dysport].

Abstract

53 patients with the syndrome of spastic torticollis (ST) were examined to assess the nature and dynamics of pain syndrome during the treatment with dysport. The patient's condition assessment was examined before and 1 month after injection of dysport using Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). The TWSTRS scale includes 3 subscales (severity of torticollis, disability and pain), each of which consists of the attributes estimated for scores. Observations showed that 1 month after injection of dysport with doses ranging from 500 to 1000 units in the affected muscles of the neck pain intensity decreased by an average of 55%, which has averaged 6,2 points of the TWSTRS pain subscale (p<0,01). Observation confirmed that pain is one of the leading complaints in patients with ST. Pathogenetic basis of the pain formation in this disease and prospects of botulinum toxin therapy in pain syndrome correction were discussed.

• Authors: Z A Zalialova, D M Abdulgalimova
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 110 Issue 11 Pt 2 Pg. 62-5 ( 2010) ISSN: 1997-7298 [Print] Russia (Federation)
• PMID: 21389941 (Publication Type: English Abstract, Journal Article)

Chemical References

• Botulinum Toxins, Type A
• abobotulinumtoxinA

Topics

• Adult
• Aged
• Botulinum Toxins, Type A (therapeutic use)
• Disability Evaluation
• Female
• Humans
• Male
• Middle Aged
• Pain (drug therapy, etiology)
• Pain Measurement
• Severity of Illness Index
• Syndrome
• Torticollis (complications, physiopathology)
• Treatment Outcome
• Young Adult