Abstract | AIMS AND BACKGROUND: METHODS: RESULTS: One terminal patient treated with pericardiocentesis died after only a few hours. All the remaining patients experienced immediate symptomatic improvement and no operative complications. At the end of the study period, 2 patients were alive at 59 and 33 months, respectively, and 4 died of disease progression at 1 to 32 months (mean, 10.5). CONCLUSIONS: Pericardiocentesis is an active necessary approach, and intrapericardial treatment with thiotepa was able to reduce pericardial effusion and to prevent its reaccumulation. The standard treatment of malignant effusion and cardiac tamponade has not yet been defined. Physicians should consider the status and the prognosis of each case.
|
Authors | Sergio Cozzi, Sergio Montanara, Annalisa Luraschi, Paola Fedeli, Paola Buscaglia, Vincenzina Amodei, Ornella Fossati, Aldo Gioria, Elisabetta Garzoli, Gianmarco Ferrari |
Journal | Tumori
(Tumori)
2010 Nov-Dec
Vol. 96
Issue 6
Pg. 926-9
ISSN: 0300-8916 [Print] United States |
PMID | 21388053
(Publication Type: Journal Article)
|
Topics |
- Adult
- Aged
- Breast Neoplasms
(complications)
- Cardiac Tamponade
(etiology, mortality, therapy)
- Female
- Humans
- Lung Neoplasms
(complications)
- Lymphoma, B-Cell
(complications)
- Male
- Middle Aged
- Pericardial Effusion
(etiology, mortality, therapy)
- Pericardiocentesis
- Survival Analysis
- Treatment Outcome
|