Abstract | OBJECTIVE: METHODS: Ninety-six patients with tubal pregnancy (mean age 21-40 years) were randomized into 3 groups for treatment with pelvic MTX injection via the posterior fornix+ mifepristone+ traditional Chinese medicine (experiment group), intramuscular MTX injection+ mifepristone+ traditional Chinese medicine (control group I), or mifepristone+traditional Chinese medicine (control group II). On days 4 and 7 of the treatment, blood β-HCG of the patients in different groups was detected, and in cases with continuous reduction of blood β-HCG or a reduction by over 15%, β-HCG was checked every week. One week after the treatment, the size of the mass was measured by B-mode ultrasound. The clearance time of β-HCG and the hospital stay of the patients were recorded. RESULTS: Twenty-nine patients in the experimental group were treated successfully, with a cure rate of 90.6%, which was significantly higher than those in the two control groups (P<0.05). The clearance time of β-HCG and hospital stay were also much shorter in the experimental group (P<0.05). CONCLUSION: Pelvic MTX injection via the posterior fornix is a convenient procedure associated with minimal complications and serves as a good alternative for treatment of tubal pregnancy.
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Authors | Xiu-li Yang, Yu-ping Cao, Zhi-hui Liu |
Journal | Nan fang yi ke da xue xue bao = Journal of Southern Medical University
(Nan Fang Yi Ke Da Xue Xue Bao)
Vol. 31
Issue 2
Pg. 377-9
(Feb 2011)
ISSN: 1673-4254 [Print] China |
PMID | 21354935
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Abortifacient Agents, Nonsteroidal
- Drugs, Chinese Herbal
- Mifepristone
- Methotrexate
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Topics |
- Abortifacient Agents, Nonsteroidal
(administration & dosage)
- Adult
- Drug Therapy, Combination
- Drugs, Chinese Herbal
(administration & dosage)
- Female
- Humans
- Injections
- Methotrexate
(administration & dosage)
- Mifepristone
(administration & dosage)
- Pelvis
- Phytotherapy
- Pregnancy
- Pregnancy, Tubal
(drug therapy)
- Vagina
- Young Adult
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