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Prevalence of specific herpes simplex virus-2 antibodies and associated factors in women of a rural town of Colombia.

Abstract
There is lack of age-specific seroprevalence surveys and identification of factors associated with herpes simplex virus type-2 seropositivity (HSV-2) in rural populations in Colombia. A random sample of 869 women was interviewed about socio-demographic aspects, sexual and reproductive history. Antibodies to HSV-2 were determined by a specific type immunoenzymatic technique (ELISA). Participants had a mean age of 38±16.1 years, 67% were married, 60% monogamous and 47% reported use of condoms. HSV-2 seroprevalence was 19.1% (95% CI: 16.6-21.9) and it was strongly associated with increasing age (Ptrend<0.001). In the logistic regression analysis, women who reported between two or three lifetime sexual partners (OR=2.4; 95% CI: 1.5-3.7), >31 years of sexual activity with regular or occasional sexual partners (OR=4.3; 95% CI: 1.2-15.7) and not using condoms with regular sexual partners (OR=2.1; 95% CI: 1.4-3.3) were more likely to be HSV-2 seropositive. The overall seroprevalence rate of women of Pueblorrico, Colombia, is lower than that reported in other Latin American countries especially in women>45 years. The difference may be explained by higher prevalence of condom use in this population or lower exposure to herpes infection in male as well as females in the past.
AuthorsClara A Sierra, Astrid M Bedoya, Sara Paris, Armando Baena, Angela M Gaviria, Carlos A Rojas, Maria P Arbelaez, Gloria I Sanchez
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene (Trans R Soc Trop Med Hyg) Vol. 105 Issue 4 Pg. 232-8 (Apr 2011) ISSN: 1878-3503 [Electronic] England
PMID21353272 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
Chemical References
  • Antibodies, Viral
Topics
  • Adult
  • Antibodies, Viral (blood)
  • Colombia (epidemiology)
  • Female
  • Herpes Genitalis (epidemiology, immunology, transmission)
  • Herpesvirus 2, Human (immunology)
  • Humans
  • Interviews as Topic
  • Physical Examination
  • Prevalence
  • Quality of Life (psychology)
  • Risk Factors
  • Rural Health
  • Seroepidemiologic Studies
  • Sexual Partners (psychology)

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