Efficacy and tolerance of nisoldipine VS propranolol in patients with essential hypertension.

Abstract

Fifty patients with essential hypertension grade I/II. (WHO) were treated with Nisoldipine (BAY K 5552) or Propranolol for 12 weeks in a single blind, randomised trial. Both drugs similarly reduced mean systolic and diastolic blood pressure. Side effects were rare and usually mild. We conclude that Nisoldipine is safe and effective in the treatment of mild essential hypertension.

• Authors: T Chamiec, B Bednarz, A Budaj, J Kłoś, H Pietrzykowska, T Zaleska, L Ceremuzyński
• Journal: Materia medica Polona. Polish journal of medicine and pharmacy (Mater Med Pol) 1990 Jul-Sep Vol. 22 Issue 3 Pg. 188-90 ISSN: 0025-5246 [Print] Poland
• PMID: 2132424 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Nisoldipine
• Propranolol

Topics

• Blood Pressure (drug effects)
• Heart Rate (drug effects)
• Humans
• Hypertension (drug therapy)
• Middle Aged
• Nisoldipine (adverse effects, therapeutic use)
• Propranolol (adverse effects, therapeutic use)