Mortality associated with ischaemic hepatitis.

Abstract

Twenty-nine patients of 18,000 inpatient admissions over a six-month period developed ischaemic hepatitis accompanied by peak aspartate aminotransferase (AST-EC 2.6.1.1) activity greater than 1,000 U/L. Seventeen of these 29 patients died either during or shortly after the episode of ischaemic hepatitis, with an overall mortality of 58.6%. Mortality was not due in any of the cases to the hepatitis but rather the underlying cause. Ischaemic hepatitis was the commonest cause of an AST activity greater than 1,000 U/L in this hospital population (29 of 52 patients i.e. 56%). This condition is more common than generally appreciated and is associated with a poor prognosis.

• Authors: P E Hickman, J M Potter
• Journal: Australian and New Zealand journal of medicine (Aust N Z J Med) Vol. 20 Issue 1 Pg. 32-4 (Feb 1990) ISSN: 0004-8291 [Print] Australia
• PMID: 2132296 (Publication Type: Journal Article)

Chemical References

• Aspartate Aminotransferases

Topics

• Aspartate Aminotransferases (blood, physiology)
• Cardiac Output, Low (complications)
• Cause of Death
• Hepatitis (blood, etiology, mortality)
• Humans
• Ischemia (blood, etiology, mortality)
• Liver (blood supply)
• Prognosis