Abstract | OBJECTIVE: We investigated the clinical characteristics of intensive insulin therapy in Japanese type 2 diabetes patients who commenced intensive insulin therapy during the in-hospital diabetes education program at Tokai university hospital. METHODS: 81 type 2 diabetes patients who received intensive insulin therapy and in-hospital diabetes education program were examined their clinical features. RESULTS: Intensive insulin therapy maintained HbA(1C) below 7% at all time points during the 2-year follow-up, though it was not necessary to increase the insulin dose, thus highlighting the clinical utility of the therapy in preventing diabetic complications. Insulin therapy could be withdrawn from more than 25% of patients. The diabetic morbid period was shorter and urinary C-peptide level at admission was higher in patients of the withdrawal group than those of the non-withdrawal group, suggesting that patients with well maintained pancreatic β cell reserve could be withdrawn from insulin therapy. CONCLUSIONS:
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Authors | Masao Toyoda, Tomoya Umezono, Makiko Abe, Keiko Kobayashi, Mayuko Kato, Katsuhiko Yoshino, Takako Kobayashi, Masaaki Miyauchi, Naoyuki Yamamoto, Moritsugu Kimura, Mayumi Maruyama, Masashi Honma, Mitsunori Yagame, Daisuke Suzuki |
Journal | The Tokai journal of experimental and clinical medicine
(Tokai J Exp Clin Med)
Vol. 33
Issue 2
Pg. 95-9
(Jul 20 2008)
ISSN: 2185-2243 [Electronic] Japan |
PMID | 21318975
(Publication Type: Journal Article)
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Chemical References |
- Blood Glucose
- C-Peptide
- Insulin
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Topics |
- Adult
- Aged
- Asian People
- Blood Glucose
(metabolism)
- C-Peptide
(urine)
- Diabetes Complications
- Diabetes Mellitus, Type 2
(drug therapy)
- Female
- Humans
- Insulin
(therapeutic use)
- Male
- Middle Aged
- Patient Education as Topic
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