Abstract | OBJECTIVE: METHODS: RESULTS: Compared with the I/R group, polysaccharides of the Euphoria Longan (Lour.) Steud could obviously reduce the neurological score, the infract volume, the brain water content, MDA content, MPO activity, TNF-? and IL-1? level, expression of Bax, and increase SOD, GSH, GSH-Px activity and expression of Bcl-2. CONCLUSION: The data suggest that polysaccharides of the Euphoria Longan (Lour.) Steud are capable of alleviating I/R injury by a mechanism that may involve decreasing oxidative stress.
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Authors | Jian Chen, Xu Chen, Jian Qin |
Journal | Brain injury
(Brain Inj)
Vol. 25
Issue 3
Pg. 292-9
( 2011)
ISSN: 1362-301X [Electronic] England |
PMID | 21280975
(Publication Type: Journal Article)
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Chemical References |
- Plant Extracts
- Polysaccharides
- Malondialdehyde
|
Topics |
- Animals
- Brain Ischemia
(drug therapy, pathology)
- Infarction, Middle Cerebral Artery
(drug therapy, pathology)
- Malondialdehyde
(metabolism, pharmacology)
- Oxidative Stress
(drug effects)
- Plant Extracts
(metabolism, therapeutic use)
- Polysaccharides
(metabolism, therapeutic use)
- Rats
- Reperfusion Injury
(drug therapy, pathology)
- Sapindaceae
(chemistry)
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