Abstract | OBJECTIVES: BACKGROUND: METHODS: RESULTS: The FFR value of the nonculprit stenoses did not change between the acute and follow-up (0.77 ± 0.13 vs. 0.77 ± 0.13, respectively, p = NS). In only 2 patients, the FFR value was higher than 0.8 at the acute phase and lower than 0.75 at follow-up. The TIMI flow, cTFC, percentage diameter stenosis, minimum lumen diameter, and index of microcirculatory resistance did not change. Left ventricular ejection fraction increased significantly in patients with STEMI (from 54 ± 13% to 57 ± 13%, p = 0.03). CONCLUSIONS: During the acute phase of acute coronary syndromes, the severity of nonculprit coronary artery stenoses can reliably be assessed by FFR. This allows a decision about the need for additional revascularization and might contribute to a better risk stratification.
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Authors | Argyrios Ntalianis, Jan-Willem Sels, Giedrius Davidavicius, Nobuhiro Tanaka, Olivier Muller, Catalina Trana, Emanuele Barbato, Michalis Hamilos, Fabio Mangiacapra, Guy R Heyndrickx, William Wijns, Nico H J Pijls, Bernard De Bruyne |
Journal | JACC. Cardiovascular interventions
(JACC Cardiovasc Interv)
Vol. 3
Issue 12
Pg. 1274-81
(Dec 2010)
ISSN: 1876-7605 [Electronic] United States |
PMID | 21232721
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Validation Study)
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Copyright | Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
Topics |
- Angioplasty, Balloon, Coronary
- Coronary Angiography
- Coronary Stenosis
(diagnosis, pathology)
- Coronary Vessels
(pathology)
- Female
- Fractional Flow Reserve, Myocardial
- Health Status Indicators
- Hemodynamics
- Humans
- Male
- Middle Aged
- Myocardial Infarction
(diagnosis, pathology, therapy)
- Prospective Studies
- Reproducibility of Results
- Statistics, Nonparametric
- Stroke Volume
- Ventricular Function, Left
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