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Minocycline-induced chemical pneumonitis and its successful treatment: a case report.

Abstract
Chemical pleurodesis is an effective treatment for persistent air leakage and secondary pneumothorax. We report the case of a 57-year-old man who presented with pneumothorax and was treated by tube thoracostomy. Because of malpositioning of the chest tube, the minocycline that was administered for pleurodesis was injected into the lung parenchyma instead, which induced chemical pneumonitis. A review of literature indicated that this is the first report of minocycline-associated chemical pneumonitis and its successful treatment.
AuthorsH-W Shih, S-L Cheng, S-C Chang, C-Y Chang
JournalInternational journal of clinical pharmacology and therapeutics (Int J Clin Pharmacol Ther) Vol. 49 Issue 1 Pg. 49-50 (Jan 2011) ISSN: 0946-1965 [Print] Germany
PMID21176726 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Minocycline
Topics
  • Anti-Bacterial Agents (adverse effects)
  • Chest Tubes
  • Humans
  • Male
  • Middle Aged
  • Minocycline (adverse effects)
  • Pneumonia (chemically induced, diagnostic imaging, therapy)
  • Radiography, Thoracic

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