Abstract | BACKGROUND: METHODS: RESULTS: The results of sputum exfoliative cytology were 27 positive in 70 samples diagnosed with lung cancer, whose sensitivity and specificity were 38.6% and 100.0% respectively. The results of sputum immunohistochemistry were 50 positive in 70 samples, with 23 positive in 29 squamous cell carcinoma and 17 positive in 26 adenocarcinoma and 10 positive in 15 small cell lung carcinoma. Sputum IHC of hnRNP B1 gave a sensitivity of 71.4% and specificity of 93.3%. Sputum IHC of hnRNP B1 was more sensitive than sputum exfoliative cytology (P < 0.05). CONCLUSIONS:
hnRNP B1 overexpresses in sputum exfoliative cells and its sensitivity is better than sputum exfoliative cytology in diagnosis of lung cancer.
|
Authors | Chi Wu, Weimin Li, Dan Xu, Wenbin Chen, Dapeng Wei, Qinghua Zhou |
Journal | Zhongguo fei ai za zhi = Chinese journal of lung cancer
(Zhongguo Fei Ai Za Zhi)
Vol. 9
Issue 5
Pg. 428-30
(Oct 20 2006)
ISSN: 1009-3419 [Print] China |
PMID | 21176464
(Publication Type: English Abstract, Journal Article)
|