Abstract |
Seventy-five men presenting with persistent urethral discharge after penicillin therapy were investigated for sexually transmitted pathogens during July - September 1987. The major aetiological agent isolated was Neisseria gonorrhoeae (58 patients (77.3%]. Penicillinase-producing N. gonorrhoeae (PPNG) accounted for 58.6% of 58 isolates. Chlamydia trachomatis was detected in 10.7% of patients and Trichomonas vaginalis in 14.7% of patients. When there is a high prevalence of PPNG, the use of penicillin as a first-line agent for therapy should be discontinued in favour of an agent active against PPNG and non-PPNG strains. Furthermore, in view of the relatively high prevalence of T. vaginalis, patients returning with persistent urethral discharge should be investigated and treated for infection with this protozoan.
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Authors | A A Hoosen, K D Coetzee, J van den Ende |
Journal | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
(S Afr Med J)
Vol. 78
Issue 4
Pg. 189-91
(Aug 18 1990)
ISSN: 0256-9574 [Print] South Africa |
PMID | 2116671
(Publication Type: Journal Article)
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Chemical References |
- Penicillin G Procaine
- Penicillin G
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Topics |
- Adolescent
- Adult
- Animals
- Chlamydia trachomatis
(isolation & purification)
- Drug Resistance, Microbial
- Gonorrhea
(drug therapy, microbiology)
- Humans
- Male
- Middle Aged
- Neisseria gonorrhoeae
(isolation & purification)
- Penicillin G
(therapeutic use)
- Penicillin G Procaine
(therapeutic use)
- Recurrence
- Trichomonas vaginalis
(isolation & purification)
- Urethritis
(drug therapy, microbiology)
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