[Palpitin--an anti-arrhythmic drug in ischemic heart disease].

Abstract

The effectiveness was assessed of the antiarrhythmic treatment with Palpitin in 30 patients with ischaemic heart disease (IHD). The control group comprised 15 patients with IHD and arrhythmia, treated with propranolol. In all patients ECG recording by Holter's method was done before the treatment and after 14 days of the treatment. The effectiveness of Palpitin was expressed as improvement in 66% of cases (reduction of ectopic beats by 75%), and in 40% of cases complete regression of arrhythmia was achieved. These results were slightly better than in the group treated with propranolol (improvement in 60% of cases). Palpitin during the treatment caused no increase in the manifestations of cardiac failure and produced no disturbances of atrioventricular conduction. Fairly frequently the patients complained about mucosal dryness and sporadically about dyspeptic symptoms, but these symptoms were not disturbing the course of the treatment.

• Authors: J Kuch, A Mamcarz, J Król, J Sawicki, W Braksator
• Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) (Wiad Lek) 1990 Jan 1-15 Vol. 43 Issue 1-2 Pg. 23-7 ISSN: 0043-5147 [Print] Poland
• Vernacular Title: Palpitin--lek przeciwarytmiczny w chorobie niedokrwiennej serca.
• PMID: 2114703 (Publication Type: English Abstract, Journal Article)

Chemical References

• Disopyramide

Topics

• Adult
• Aged
• Arrhythmias, Cardiac (drug therapy, etiology)
• Coronary Disease (complications, drug therapy)
• Disopyramide (adverse effects, analogs & derivatives, therapeutic use)
• Electrocardiography, Ambulatory
• Female
• Humans
• Male
• Middle Aged