Antibiotic prophylaxis in the placement of totally implanted central venous access ports.

Abstract

BACKGROUND:

Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP) has not been studied. This retrospective review compared the rate of catheter-related infections (CRIs) with and without perioperative antibiotics.

METHODS:

This was a single-center study that compared patients treated with and without a single dose of antibiotics during CVAP placement. CRIs were defined as a patient treated with antibiotics for port site induration, positive blood cultures, or suspicion of infection that led to port removal within 30 days of placement.

RESULTS:

CVAP were placed in 459 patients, 103 of whom (22.4%) received antibiotic prophylaxis. Surgical technique and patient demographics were similar to those patients not receiving antibiotics (356). All 9 (2%) CRIs occurred in the non-prophylactic antibiotic group (P = .218), with 5 infections resulting in port removal.

CONCLUSIONS:

Single-dose perioperative antibiotics may decrease CVAP infection rates and should be studied further in a prospective randomized trial.

• Authors: Courtney L Scaife, Molly E Gross, Mary C Mone, Heidi J Hansen, Codi L Litz, Edward T Nelson, Clayton J Anderson, Graham Wagner, Ute Gawlick, Edward W Nelson
• Journal: American journal of surgery (Am J Surg) Vol. 200 Issue 6 Pg. 719-22; disussion 722-3 (Dec 2010) ISSN: 1879-1883 [Electronic] United States
• PMID: 21146010 (Publication Type: Controlled Clinical Trial, Journal Article)
• Copyright: Copyright © 2010 Elsevier Inc. All rights reserved.

Chemical References

• Antineoplastic Agents

Topics

• Antibiotic Prophylaxis
• Antineoplastic Agents (administration & dosage)
• Catheter-Related Infections (prevention & control)
• Catheterization, Central Venous
• Catheters, Indwelling
• Female
• Humans
• Jugular Veins
• Male
• Middle Aged
• Subclavian Vein