Abstract | BACKGROUND: METHODS: Thirty-seven men with metabolic syndrome completed an open and balanced crossover study. Treatment periods lasted for 6 to 8 weeks and they were separated from each other with an eight-week washout period. Subjects maintained their normal dietary habits and physical activity without major variations. The daily fat adjunct consisted either of 37.5 grams of butter or 35 mL of Virgino R CPTRO. Participants were asked to spread butter on bread on the butter period and to drink CPTRO on the oil period. The fat adjunct was used as such without heating or frying. RESULTS: Compared to butter, administration of CPTRO was followed by a reduction of total cholesterol by 8% (p < 0.001) and LDL cholesterol by 11% (p < 0.001). The level of oxidized LDL was 16% lower after oil period (p = 0.024). Minimal differences in arterial elasticity were not statistically significant. CONCLUSION:
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Authors | Ari Palomäki, Hanna Pohjantähti-Maaroos, Marja Wallenius, Päivi Kankkunen, Heikki Aro, Sari Husgafvel, Juha-Matti Pihlava, Kalevi Oksanen |
Journal | Lipids in health and disease
(Lipids Health Dis)
Vol. 9
Pg. 137
(Dec 01 2010)
ISSN: 1476-511X [Electronic] England |
PMID | 21122147
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cholesterol, HDL
- Cholesterol, LDL
- Fatty Acids, Monounsaturated
- Fatty Acids, Omega-3
- Lipoproteins, LDL
- Plant Oils
- Rapeseed Oil
- oxidized low density lipoprotein
- Butter
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Topics |
- Administration, Oral
- Adult
- Aged
- Arteries
(physiopathology)
- Brassica napus
- Butter
- Cholesterol, HDL
(blood)
- Cholesterol, LDL
(blood)
- Diet
- Elasticity
- Europe
- Fatty Acids, Monounsaturated
- Fatty Acids, Omega-3
(administration & dosage, metabolism)
- Humans
- Lipoproteins, LDL
(blood)
- Male
- Metabolic Syndrome
(blood, diet therapy, physiopathology)
- Middle Aged
- Plant Oils
(administration & dosage, metabolism)
- Rapeseed Oil
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