Alopecia in vitamin D-dependent rickets type II responding to 1α-hydroxycholecalciferol.

Abstract

A 4-year-old boy presented with rickets, alopecia and macrocephaly along with elevated serum levels of 1,25(OH)₂D₃ which was diagnostic of vitamin D-dependent rickets type II. The rickets responded to conventional doses of 1α-hydroxycholecalciferol together with oral calcium supplement and there was also improvement in the alopecia. In patients with vitamin D-dependent rickets type II with alopecia, although rickets improves with treatment, improvement in alopecia has not been reported before.

• Authors: V Kumar, M Kumar, M Yadav
• Journal: Annals of tropical paediatrics (Ann Trop Paediatr) Vol. 30 Issue 4 Pg. 329-33 ( 2010) ISSN: 1465-3281 [Electronic] England
• PMID: 21118628 (Publication Type: Case Reports, Journal Article)

Chemical References

• Hydroxycholecalciferols
• Vitamin D
• Calcium
• alfacalcidol

Topics

• Alopecia (complications, drug therapy)
• Calcium (administration & dosage, therapeutic use)
• Child, Preschool
• Familial Hypophosphatemic Rickets (complications, diagnostic imaging, drug therapy)
• Humans
• Hydroxycholecalciferols (administration & dosage, therapeutic use)
• Male
• Megalencephaly (complications, drug therapy)
• Radiography
• Treatment Outcome
• Vitamin D (metabolism)