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A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience.

Abstract
We report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.
AuthorsP J Trivedi, P S Patel, M M Brahmbhatt, B P Patel, S B Gajjar, E N Dalal, S N Shukla, P M Shah, S R Bakshi
JournalIndian journal of human genetics (Indian J Hum Genet) Vol. 15 Issue 3 Pg. 137-9 (Sep 2009) ISSN: 0971-6866 [Print] India
PMID21088719 (Publication Type: Journal Article)

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