[Malignant insuloma. Evaluation of the response to treatment with streptozotocin, using selective arteriography of the celiac axis].

Abstract

A patients with metastatic insulin-producing islet-cell carcinoma has been treated with Streptozotocin intravenously and studied by selective celiac angiography during treatment. A 50% decrease of the tumor's size has been demonstrated by this technique after a total dose of 19 grams of the drug together with return to normal of the serum-insulin and blood-glucose values. The usefulness of angiography in evaluating the tumor response to Streptozotocin and in managing chemotherapy is discussed.

• Authors: G Neri, A Caresano, F Croce
• Journal: Minerva medica (Minerva Med) Vol. 69 Issue 29 Pg. 1983-90 (Jun 09 1978) ISSN: 0026-4806 [Print] Italy
• Vernacular Title: Insuloma maligno. Valutazione della risposta alla terapia con streptozotocina mediante arteriografia selettiva del tripode celiaco.
• PMID: 210429 (Publication Type: Case Reports, Journal Article)

Chemical References

• Streptozocin

Topics

• Adenoma, Islet Cell (diagnostic imaging, drug therapy)
• Angiography
• Celiac Artery (diagnostic imaging)
• Drug Evaluation
• Female
• Humans
• Middle Aged
• Pancreatic Neoplasms (diagnostic imaging, drug therapy)
• Streptozocin (therapeutic use)