Abstract | OBJECTIVE:
Adiponectin and resistin have been postulated to play a role in the regulation of energy metabolism during pregnancy. However, relationship of adiponectin and resistin levels in umbilical serum, maternal serum and placenta with neonatal birth weight remains to be poorly understood. The purpose of the study was to clarify the correlations between adiponectin and resistin levels and neonatal birth weight. METHODS: RESULTS: Serum adiponectin and resistin levels were significantly increased in control women compared with that in macrosomia mothers, but significantly decreased compared with that in FGR mothers. The levels of adiponectin and resistin in control babies were significantly higher than that in macrosomic babies, whereas significantly lower than that in FGR babies. The placental expressions of adiponectin and resistin in macrosomia, control and FGR group were gradually elevated, and there was a significant difference between them. Umbilical serum adiponectin levels and placental adiponectin expression were inversely correlated with birth weight. Umbilical serum levels and placental expression of resistin had positive correlation with maternal serum resistin and negative correlation with birth weight. In addition, maternal serum resistin levels were inversely correlated with birth weight. CONCLUSION:
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Authors | Jing Wang, Li-Xin Shang, Xing Dong, Xin Wang, Nan Wu, Shu-He Wang, Fang Zhang, Li-Ming Xu, Ying Xiao |
Journal | The Australian & New Zealand journal of obstetrics & gynaecology
(Aust N Z J Obstet Gynaecol)
Vol. 50
Issue 5
Pg. 432-8
(Oct 2010)
ISSN: 1479-828X [Electronic] Australia |
PMID | 21039376
(Publication Type: Journal Article)
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Copyright | © 2010 The Authors. Australian and New Zealand Journal of Obstetrics and Gynaecology © 2010 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists. |
Chemical References |
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Topics |
- Adiponectin
(blood, metabolism)
- Adult
- Birth Weight
- Case-Control Studies
- Female
- Fetal Blood
(metabolism)
- Fetal Growth Retardation
(blood)
- Fetal Macrosomia
(blood)
- Humans
- Infant, Newborn
- Placenta
(metabolism)
- Pregnancy
- Resistin
(blood, metabolism)
- Statistics, Nonparametric
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