Topically applied levobunolol does not cause changes in the corneal endothelium.

Abstract

The corneal endothelium was examined in ten patients suffering from ocular hypertension before, during and after four months of topical levobunolol treatment. The untreated fellow eye served as a control. The number of endothelial cells, determined with a McIntyre eyepiece and an Eisner's contact lens, was not affected by levobunolol therapy. In addition, the morphology of the cell did not appear to be affected by the drug.

• Authors: R Fusco, A Del Prete, A Gravina, G Nieto
• Journal: Documenta ophthalmologica. Advances in ophthalmology (Doc Ophthalmol) 1990-1991 Vol. 76 Issue 3 Pg. 273-7 ISSN: 0012-4486 [Print] Netherlands
• PMID: 2103529 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Levobunolol

Topics

• Administration, Topical
• Aged
• Endothelium, Corneal (drug effects, pathology)
• Female
• Humans
• Levobunolol (administration & dosage, pharmacology, therapeutic use)
• Male
• Ocular Hypertension (drug therapy, pathology)