Abstract |
Vitamin A and synthetic retinoids have recently been used increasingly in a variety of health related concerns. Hepatic toxicity is an uncommon but serious side-effect of several Vitamin A derivatives which may lead to cirrhosis. This review will focus on the clinical and pathologic findings of hepatic involvement in chronic hypervitaminosis A and on the evidence concerning the potential hepatotoxicity of currently available synthetic retinoids.
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Authors | M B Fallon, J L Boyer |
Journal | Journal of gastroenterology and hepatology
(J Gastroenterol Hepatol)
1990 May-Jun
Vol. 5
Issue 3
Pg. 334-42
ISSN: 0815-9319 [Print] Australia |
PMID | 2103414
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Chemical and Drug Induced Liver Injury
(etiology, pathology)
- Etretinate
(pharmacokinetics, toxicity)
- Female
- Humans
- Hypervitaminosis A
(etiology, pathology)
- Isotretinoin
(pharmacokinetics, toxicity)
- Liver
(drug effects)
- Male
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