[Direct immunofluorescence in the study of palatal mucosal changes compatible with chronic atrophic candidiasis in mucosal supported complete denture wearers].

Abstract	Histopathology by hematoxilin-eosin (HE) and periodic acid Schiff (PAS), concomitant direct immunofluorescence (DI) against total human immunoglobulins and against Candida albicans, was effectuated in 25 persons dentures wearers. In 5 persons without chronic athrofic candidiasis (CAC) clinical signals in the palate the HE showed wise inflammatory elements in the connective tissue and the PAS marked the continuous basal layer, the intra-cellular grains of granular layer and the uniform parakeratin on epithelial surface. In 20 others, with palatal signals of CAC, in the HE was frequent the features encountered in Candida infected and PAS revealed, beside descontinuous lamina basal and epithelial surface covered by tide and discontinuous parakeratin, the presence of round bodies few largers that presents in the granular layer, casually isolated in the medial portion of ret pegs and connective papillae. In the first 5 persons the DI against total human immunoglobulins not showed signals of the humoral immunologic phenomena, the same was valid to others 20 patients with CAC clinical aspects. However the DI with conjugate against C. albicans in the 20 cases with CAC signals revealed suitable aspects of the structures assumed by Candida in tissues. Cultures of samples obtained of the persons with CAC signals was positive in 100% to Candida, 70% presumptively albicans, against 80% of positiviness to generus Candida, 67% presumptively albicans, in the persons without CAC signals.
Authors	L A Guimarães Cabral
Journal	Revista de odontologia da UNESP (Rev Odontol UNESP) Vol. 19 Issue 1 Pg. 125-39 ( 1990) ISSN: 0101-1774 [Print] Brazil
Vernacular Title	Emprego da imunofluorescência direta no estudo das alterações de mucosa de palato, compatíveis com candidíase atrófica crônica, em indivíduos portadores de próteses dentárias totais muco-suportadas.
PMID	2099541 (Publication Type: Journal Article, Review)
Topics	Candida albicans (immunology) Candidiasis, Oral (diagnosis, immunology) Chronic Disease Denture, Complete, Upper Dentures (adverse effects) Female Humans Male Microscopy, Fluorescence Mouth Mucosa Palate Stomatitis, Denture (microbiology)

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